Learning Targets

• To appreciate ESC and NICE guidelines for the investigation of patients presenting with stable chest pain
• To compare the strengths and weaknesses of non-invasive imaging tests for the investigation of patients presenting with stable chest pain
• To select appropriate stress for coronary functional imaging according to patient characteristics. 
• To review aspects of the cost-effectiveness of non-invasive tests of coronary function
• When evaluating a patient with suspected SCAD it is essential to calculate the pre-test probability to select the appropriate test.
• Regadenoson is currently the stress test of choice in patients with suspected SCAD, with severe chronic obstructive pulmonary disease and who cannot perform a good exercise test.
• A stress test performed with Regadenoson has a diagnostic and prognostic yield comparable to other vasodilators or an exercise test.
• Regadenoson is by far the most practical pharmacological stress protocol (independent of the weight of the patient, short infusion time, few side effects, etc.)
• Indications for Regadenoson in daily practice
• Correct use of Regadenoson
• Procedure for possible complications
• For diagnostic purpose of CAD, maximal stress is required
• Whenever 85% maximal predicted HR is not achievable, the combination of exercise with a coronary vasodilator agent is advised
• Regadenoson offers the possibility to decide upon the opportunity to administrate the vasodilator agent according to the patients’ actual exercise abilities  with only a 30 sec prolongation of the duration of exercise